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Search Results for " serine protease inhibitor "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

TargetMolキット

カタログ番号	製品名	別名	ターゲット
T8350	TPCK		Proteasome
	TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis		Proteasome
T13408	ZK824190		Others , Serine Protease
	ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively).		Others , Serine Protease
TP1277	Bradykinin		Endogenous Metabolite , Bradykinin Receptor
	Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor. Bradykinin is a physiol...		Endogenous Metabolite , Bradykinin Receptor
T13257	Upamostat		PAI-1 , Serine/threonin kinase , Serine Protease
	Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.		PAI-1 , Serine/threonin kinase , Serine Protease
T11666	IPR-803		Serine/threonin kinase
	IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM.		Serine/threonin kinase
T4058	R-IMPP		Others , Serine/threonin kinase
	R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.		Others , Serine/threonin kinase
T10547	BioE-1115		Serine/threonin kinase , Casein Kinase
			Serine/threonin kinase , Casein Kinase
T11885	LSP-249		Others
	LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell.		Others
T7017	WNK463		Serine/threonin kinase
	WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).		Serine/threonin kinase
T5456	WNK-IN-11	Allosteric WNK Kinase Inhibitor	Serine/threonin kinase
	WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)		Serine/threonin kinase
T4524	SBC-110736	SBC110736	Others , Serine/threonin kinase
	SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor		Others , Serine/threonin kinase
T9920	Evolocumab		Others
	Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 Proprotein Convertase Subtilisin Kexin Type 9).		Others
T14358	Avoralstat	BCX4161	Others
	Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.		Others
T9276	SBC-115337		Others , Serine/threonin kinase
	SBC-115337 is a PCSK9 inhibitor.		Others , Serine/threonin kinase
T8936	Proteinase K	proteinase K for tritirachium album,Protease K	Others
	Proteinase K (proteinase K for tritirachium album) is a nonspecific serine protease that is useful for general digestion of proteins. It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt c...		Others
T8645	PF-06446846		Others
	PF 06446846 is a potent and selective PCSK9 inhibitor		Others
T2626	SBC-115076	SBC115076	Others , Serine/threonin kinase
	SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.		Others , Serine/threonin kinase
T1954	SRPIN340	SRPK inhibitor	Virus Protease , Serine/threonin kinase
	SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).		Virus Protease , Serine/threonin kinase
T6370	AEBSF hydrochloride	AEBSF HCl,Pefabloc SC	Thrombin , Serine Protease , Influenza Virus
	AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.		Thrombin , Serine Protease , Influenza Virus
T8676	FOY 251		Others , Serine/threonin kinase , SARS-CoV
	FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.		Others , Serine/threonin kinase , SARS-CoV
T3359	Aprotinin	Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin	Others , Serine Protease , Influenza Virus , Proteasome
	Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat...		Others , Serine Protease , Influenza Virus , Proteasome
T8362	Benzamidine hydrochloride	Benzamidine HCl	Serine/threonin kinase , Serine Protease
	Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).		Serine/threonin kinase , Serine Protease
T31206	Darexaban	YM 150,Darexaban, Tanexaban,YM150	Factor Xa
	Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati...		Factor Xa
T2392	Nafamostat mesylate	FUT-175	Apoptosis , Serine/threonin kinase , SARS-CoV , Serine Protease
	Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
T19763	Cetraxate hydrochloride	DV-1006,DV 1006,Cetraxate HCl,DV1006	Serine/threonin kinase
	Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.		Serine/threonin kinase
T2391	Camostat mesylate	FOY-S980,FOY305,Camostat mesilate	Serine/threonin kinase , SARS-CoV , Sodium Channel
	Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.		Serine/threonin kinase , SARS-CoV , Sodium Channel
T9268	Ulinastatin		Others
	Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.		Others
T6190	Telaprevir	VX-950,LY-570310,Incivek,MP-424	HCV Protease , SARS-CoV
	Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).		HCV Protease , SARS-CoV
T13568L	BCX 1470 hydrochloride	BCX 1470 hydrochloride(217099-43-9 Free base),BCX1470 HCl	Serine Protease , Complement System
	BCX 1470 hydrochloride is a potent serine protease inhibitor with anti-inflammatory activity that inhibits the ester hydrolysis and haemolytic activity of factor D and C1s, and can be used to study oedema.		Serine Protease , Complement System
T4317	PF 429242		NPC1L1 , Lipid
	PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rat...		NPC1L1 , Lipid
TP1792L	KKI-5 acetate(97145-43-2 free base)		Serine Protease
	KKI-5 acetate is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.		Serine Protease
T60085	MM3122	GTPL11533,MM-3122,Ac-GQFR-kbt	SARS-CoV
	MM3122 (MM-3122) is a selective type II transmembrane serine protease (TMPRSS2) inhibitor, IC50 = 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells.		SARS-CoV
T76870	Narsoplimab	OMS 721	SARS-CoV
	Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2) inhibitor that binds MASP-2 and prevents lectin pathway ac...		SARS-CoV
T3226	Paritaprevir	ABT-450,Veruprevir	HCV Protease
	Paritaprevir (ABT-450) is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3 and 4A (NS3/NS4A), with potential activity again...		HCV Protease
T22619	Butabindide oxalate		Others
	CCK-inactivating serine protease (tripeptidyl peptidase II) inhibitor		Others
T23052	Nafamostat		Others
	Nafamostat is a synthetic serine protease inhibitor and is an anticoagulant.		Others
T23051	Nafamostat hydrochloride		Others
	Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant.		Others
T70110	CVS-1578
	CVS-1578 is a potent serine protease inhibitor, targeting the S2S3 thrombin and FXa subsites.
T10082	DPP-IV-IN-1		Others
	DPP-IV-IN-1 is an effective inhibitor of dipeptidyl peptidase IV (DPP-IV), a serine protease (IC50: 4.6 nM).		Others
T28241	Ono 3403	Ono3403,Ono-3403
	Ono 3403 is a synthetic serine protease inhibitor. Ono 3403 inhibits lipopolysaccharide-induced tumor necrosis factor-alpha and nitric oxide production. ONO-3403 also has an antitumor effect on malignant tumors.
T6564L	Leupeptin	Leupeptin Ac-LL,NK-381
	Leupeptin is a competitive protease inhibitor produced by actinomycetes. Leupeptin can inhibit cysteine, serine and threonine peptidases. Leupeptin inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), ...
T71601	CU-2010
	CU-2010 is a synthetic serine protease inhibitor with antifibrinolytic and anticoagulant properties. CU-2010 dose-dependently reduces postoperative blood loss and improves postischemic recovery after cardiac surgery in a...
T14555	BI-1230		HCV Protease
	BI-1230 is a potent inhibitor of HCV NS3 protease, exhibiting efficacy in the low nanomolar range, and notably suppresses viral replication. This compound demonstrates high selectivity, distinguishing effectively between...		HCV Protease
TP1792	KKI-5
	KKI 5 is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.
T69035	Camostat free base
	Camostat, also known as FOY 305, is a serine protease inhibitor. Camostat is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or...
T11269	FD-IN-1		Others
	FD-IN-1 is a factor D (FD) inhibitor with an IC50 of 12 nM.FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5μM, respectively. Complement FD, a highly specific S1 serine protease, plays a...		Others
T65212	β-Glycerophosphate Disodium Salt Hydrate (2:1:4)
	β-Glycerophosphate Disodium Salt Hydrate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers often used in combination with other phosphatase/protease inhibitors for broad spectrum inhib...
T69297	Leupeptin HCl
	Leupeptin is a naturally occurring protease inhibitor that can inhibit cysteine, serine and threonine peptidases. Leupeptin is an organic compound produced by actinomycetes. Leupeptin inhibits serine proteinases (trypsin...
T80094	Dansyl-Glu-Gly-Arg-Chloromethylketone
	Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activated porcine factor IX [1].
TP1656	VIR-165
	VIR-165 is a modified form of virus inhibitory peptide (VIRIP), which corresponds to residues 353 to 372 of C-proximal region of human alpha1-antitrypsin, the most abundant circulating serine protease inhibitor. VIRIP in...

Compounds

Target: Others, Serine Protease

Bradykinin

TP1277

Synonym:

Target: Endogenous Metabolite, Bradykinin Receptor

Upamostat

T13257

Synonym:

Target: PAI-1, Serine/threonin kinase, Serine Protease

IPR-803

T11666

Synonym:

Target: Serine/threonin kinase

R-IMPP

T4058

Synonym:

Target: Others, Serine/threonin kinase

BioE-1115

T10547

Synonym:

Target: Serine/threonin kinase, Casein Kinase

Target: Serine/threonin kinase

WNK-IN-11

T5456

Synonym: Allosteric WNK Kinase Inhibitor

Target: Serine/threonin kinase

SBC-110736

T4524

Synonym: SBC110736

Target: Others, Serine/threonin kinase

Target: Others, Serine/threonin kinase

Proteinase K

T8936

Synonym: proteinase K for tritirachium album,Protease K

Target: Others, Serine/threonin kinase

SRPIN340

T1954

Synonym: SRPK inhibitor

Target: Virus Protease, Serine/threonin kinase

AEBSF hydrochloride

T6370

Synonym: AEBSF HCl,Pefabloc SC

Target: Thrombin, Serine Protease, Influenza Virus

FOY 251

T8676

Synonym:

Target: Others, Serine/threonin kinase, SARS-CoV

Aprotinin

T3359

Synonym: Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin

Target: Others, Serine Protease, Influenza Virus, Proteasome

Benzamidine hydrochloride

T8362

Synonym: Benzamidine HCl

Target: Serine/threonin kinase, Serine Protease

Darexaban

T31206

Synonym: YM 150,Darexaban, Tanexaban,YM150

Target: Apoptosis, Serine/threonin kinase, SARS-CoV, Serine Protease

Cetraxate hydrochloride

T19763

Synonym: DV-1006,DV 1006,Cetraxate HCl,DV1006

Target: Serine/threonin kinase

Camostat mesylate

T2391

Synonym: FOY-S980,FOY305,Camostat mesilate

Target: Serine/threonin kinase, SARS-CoV, Sodium Channel

Synonym: VX-950,LY-570310,Incivek,MP-424

Target: HCV Protease, SARS-CoV

BCX 1470 hydrochloride

T13568L

Synonym: BCX 1470 hydrochloride(217099-43-9 Free base),BCX1470 HCl

Target: Serine Protease, Complement System

PF 429242

T4317

Synonym:

Target: NPC1L1, Lipid

KKI-5 acetate(97145-43-2 free base)

TP1792L

Synonym:

Target: Serine Protease

MM3122

T60085

Synonym: GTPL11533,MM-3122,Ac-GQFR-kbt

Synonym: ABT-450,Veruprevir

Target: HCV Protease

Nafamostat hydrochloride

Synonym: Ono3403,Ono-3403

Target:

Leupeptin

T6564L

Synonym: Leupeptin Ac-LL,NK-381

Target: HCV Protease

β-Glycerophosphate Disodium Salt Hydrate (2:1:4)

Dansyl-Glu-Gly-Arg-Chloromethylketone

カタログ番号	製品名	ターゲット
TN2082	Pinostrobin	Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF
	Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress...	Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF
T5S0689	Demethylwedelolactone	Serine Protease
	Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells.	Serine Protease
T4915	β-Glycerophosphate disodium salt hydrate	Phosphatase , Endogenous Metabolite
	β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It func...	Phosphatase , Endogenous Metabolite
T75648	Rivulariapeptolides 1155
	Rivulariapeptolides 1155 is a potent serine protease inhibitor, exhibiting inhibitory concentrations (IC50s) of 41.84 nM, 4.94 nM, and 56.54 nM against chymotrypsin, elastase, and proteinase K, respectively [1].
T75649	Rivulariapeptolides 1185
	Rivulariapeptolides 1185, a highly potent and selective serine protease inhibitor, exhibits IC50 values of 13.17 nM for chymotrypsin, 23.59 nM for elastase, and 55.26 nM for proteinase K [1].
T75652	Molassamide B
	Molassamide B, a serine protease inhibitor, exhibits potent inhibitory activity, as evidenced by its IC50 values of 24.65 nM against chymotrypsin, 11.69 nM against elastase, and 5.42 nM against proteinase K [1].
T75651	Rivulariapeptolides 988
	Rivulariapeptolides 988 demonstrates significant potency and selectivity as a serine protease inhibitor, exhibiting IC50 values of 95.46 nM for chymotrypsin, 15.29 nM for elastase, and 85.50 nM for proteinase K [1].
T75650	Rivulariapeptolides 1121
	Rivulariapeptolides 1121 is a potent and selective serine protease inhibitor, demonstrating IC50 values of 35.52 nM for chymotrypsin, 13.24 nM for elastase, and 48.05 nM for proteinase K [1].

天然物製品

Pinostrobin

TN2082

Synonym:

Target: Beta Amyloid, IL Receptor, Serine/threonin kinase, TNF

Demethylwedelolactone

T5S0689

Synonym:

Target: Serine Protease

β-Glycerophosphate disodium salt hydrate

T4915

Synonym:

Target: Phosphatase, Endogenous Metabolite

Rivulariapeptolides 1155

T75648

Synonym:

Target:

Rivulariapeptolides 1185

Rivulariapeptolides 988

T75651

Synonym:

Target:

Rivulariapeptolides 1121

T75650

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01253	Serpin A3N Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Serine protease inhibitor A3N(Serpin A3N) is a serine protease inhibitor that is structurally related to α1 antichymotrypsin encoded by the SERPINA3 gene. Serpin A3N is highly expressed in brain, testis, lung, thymus, an...
TMPJ-01282	Serpin B12 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular f...
TMPJ-00452	Serpin A1a Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Serpin A1a is also known as alpha-1-antitrypsin, is a member of the serpin superfamily of serine proteinase inhibitors that are involved in the regulation of a number of proteolytic processes. Its primary target is elast...
TMPJ-00490	Serpin A5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i...
TMPJ-01069	Serpin A1e Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-...
TMPJ-01083	Serpin E2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea...
TMPJ-00733	SPINK1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A dise...
TMPJ-01032	SPINK7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serine protease inhibitor Kazal-type 7(SPINK7) is a secreted protein, that in humans is encoded by the SPINK7 gene. SPINK7 contains 1 Kazal-like domain. SPINK7 is probably serine protease inhibitor. Recombinant human SPI...
TMPJ-00262	Serpin A12 Protein, Human, Recombinant (GST)	Human	E. coli
	Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of ...
TMPY-02078	HtrA2/Omi Protein, Human, Recombinant (His)	Human	E. coli
	Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ...
TMPY-01897	PRSS3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPY-01841	Serpin I2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPY-01855	Serpin A10 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Protein Z-dependent protease inhibitor, also known as PZ-dependent protease inhibitor, SERPINA1 and ZPI, is a secreted protein that belongs to the serpin family. It is expressed by the liver and secreted in plasma. SERPI...
TMPY-01589	Serpin B10 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPH-02408	SPI Protein, Lentinula edodes, Recombinant (His)	Lentinula edodes	E. coli
	Serine protease inhibitor. Active against beta-trypsin and alpha-chymotrypsin with dissociation constants of 0.35 nM and 40 nM respectively. Inhibits factor XIa, but not other enzymes involved in coagulation and fibrinol...
TMPJ-00625	Serpin E1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. I...
TMPJ-01320	BSSP-4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial c...
TMPY-01893	Serpin A12 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin,...
TMPK-00194	TFPI Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and...
TMPK-00195	TFPI Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and...
TMPY-01909	Elafin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein ...
TMPH-02897	SPINK1 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.; In the male reproductive tract, binds to sperm heads where it modulat...
TMPY-01632	Serpin B4 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPH-02834	PAI-1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-reg...
TMPH-02898	SPINK2 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defe...
TMPY-01814	GASP-1/WFIKKN2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2, also known as Growth and differentiation factor-associated serum protein 1, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-relat...
TMPJ-00265	Serpin F1 Protein, Mouse, Recombinant	Mouse	E. coli
	Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and ...
TMPY-06585	C1s Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses. The classical complement pathway is triggered by C1, a complex comp...
TMPJ-00891	Kallikrein 2/KLK2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave ...
TMPJ-00302	Serpin F2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver c...
TMPY-01303	Serpin A3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be...
TMPJ-00502	Serpin G1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine protease inhibitor protein...
TMPH-02832	Serpin A5 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extr...
TMPJ-00505	Serpin A1 Protein, Human, Recombinant (aa 25-418, His)	Human	HEK293 Cells
	Serpin A1 is a prototype member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in hepatocytes, and to a lesser extent,...
TMPJ-00796	Serpin E2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal panc...
TMPY-02712	Serpin B3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was orig...
TMPY-01711	Serpin B2 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPY-01551	Serpin B8 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPY-00818	Granzyme H/GZMH Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes...
TMPY-02014	Coagulation factor VII/F7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is...